Welcome to SwissRegulon ,
SwissRegulon is a repository of datbases and bioinformatic tools related to transcription regulatory processes and includes:
- SwissRegulon: A database of genome-wide annotations of regulatory sites. We currently have annotations for 17 prokaryotes and 3 eukaroytes in our collection.
- Phylogibbs: An algorithm for inferring regulatory motifs and regulatory sites from collections of DNA sequences, including multiple alignments of orthologous sequences from related organisms. Phylogibbs uses a rigorous Bayesian approach that combines search for overrepresented sequence-motifs with sequence conservation analysis of the putative sites for these motifs.
- MARA: Motif Activity Response Analysis is a free online tool that models genome-wide expression data in terms of our genome-wide annotations of regulatory sites. For an given input expression data-set it infers the key transcription regulators, their sample-dependent activities, and their genome-wide targets.
- TCS: A data-base of predicted two-component signalling interactions across bacterial genomes.